Suicide is the second leading cause of death among adolescents. Historically, when compared to Black and Latinx youth, White youth have higher rates of death by suicide. However, recent data suggest that Black and Latinx youth have the greatest increase in deaths by suicide and that yearly prevalence rates of suicide attempts are also much higher for Black and Latinx youth. Understanding predictors of suicide attempts within the broader context of suicide prevention is key as suicide attempts remain to this day, a key predictor of death by suicide for youth. To date, most work examining risk factors for self-injurious thoughts and behaviors (SITBs) have neglected to examine the effect of experiencing racial discrimination, despite well-established evidence that this race-related stressor is the most fundamental cause of adverse mental health outcomes in ethnoracially minoritized groups. In addition, most research to date that has examined key risk factors for SITBs has largely neglected to consider the direct and indirect effects of interpersonal racism on suicide. The rising trends in deaths by suicide and suicide attempts for Black and Latinx adolescents, and the current sociopolitical climate in the U.S. create a unique and timely opportunity to test the impact of perceived discrimination on suicide among ethnoracially minoritized adolescents. The current mixed-method study will examine the pathways between perceived racial discrimination and SITBs among ethnoracially minoritized adolescents presenting to UCLA’s Child and Adolescent Psychiatric Services. Another key aim of this study is to elucidate protective processes among ethnoracially minoritized youth such as their perceived social support, access to mental health services, and medication management. A better understanding of risk and protective processes will improve both detection of suicide risk and identification of viable treatment targets, which may help mitigate the current elevated rates of suicide attempt among ethnoracially minoritized youth, including Black and Latinx youth.